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The two detectives stared at him in amazement.

"I have now in my hands," my companion said, confidently, "all the threads which have formed such a tangle.

There are, of course, details to be filled in, but I am as certain of all the main facts, from the time that Drebber parted from Stangerson at the station, up to the discovery of the body of the latter, as if I had seen them with my own eyes.

I will give you a proof of my knowledge.

Could you lay your hand upon those pills?"

"I have them," said Lestrade, producing a small white box; "I took them and the purse and the telegram, intending to have them put in a place of safety at the Police Station. It was the merest chance my taking these pills, for I am bound to say that I do not attach any importance to them."

"Give them here," said Holmes. "Now, Doctor," turning to me, "are those ordinary pills?"

They certainly were not. They were of a pearly grey colour, small, round, and almost transparent against the light. "From their lightness and transparency, I should imagine that they are soluble in water," I remarked.

"Precisely so," answered Holmes. "Now would you mind going down and fetching that poor little devil of a terrier which has been bad so long, and which the landlady wanted you to put out of its pain yesterday."

I went downstairs and carried the dog upstair in my arms. It's laboured breathing and glazing eye showed that it was not far from its end. Indeed, its snow-white muzzle proclaimed that it had already exceeded the usual term of canine existence. I placed it upon a cushion on the rug.

"I will now cut one of these pills in two," said Holmes, and drawing his penknife he suited the action to the word.

"One half we return into the box for future purposes.

The other half I will place in this wine glass, in which is a teaspoonful of water.

You perceive that our friend, the Doctor, is right, and that it readily dissolves."

"This may be very interesting," said Lestrade, in the injured tone of one who suspects that he is being laughed at, "I cannot see, however, what it has to do with the death of Mr. Joseph Stangerson."

"Patience, my friend, patience! You will find in time that it has everything to do with it. I shall now add a little milk to make the mixture palatable, and on presenting it to the dog we find that he laps it up readily enough."

As he spoke he turned the contents of the wine glass into a saucer and placed it in front of the terrier, who speedily licked it dry.

Sherlock Holmes' earnest demeanour had so far convinced us that we all sat in silence, watching the animal intently, and expecting some startling effect.

None such appeared, however.

The dog continued to lie stretched upon the cushion, breathing in a laboured way, but apparently neither the better nor the worse for its draught.

Holmes had taken out his watch, and as minute followed minute without result, an expression of the utmost chagrin and disappointment appeared upon his features.

He gnawed his lip, drummed his fingers upon the table, and showed every other symptom of acute impatience.

So great was his emotion, that I felt sincerely sorry for him, while the two detectives smiled derisively, by no means displeased at this check which he had met.

"It can't be a coincidence," he cried, at last springing from his chair and pacing wildly up and down the room; "it is impossible that it should be a mere coincidence.

The very pills which I suspected in the case of Drebber are actually found after the death of Stangerson.

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